Key Advantages

  • Over 70 markers
  • Accurate evaluation of intestinal yeast and bacteria
  • Includes markers for oxalates
  • Identify correlation to multiple select disorders


The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient’s overall health with over 70 markers. It provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.

Great Plains’ Organic Acids Test also includes markers for vitamin and mineral levels, oxidative stress, neurotransmitter levels, and is the only OAT to include markers for oxalates, which are highly correlated with many chronic illnesses.

If abnormalities are detected using the OAT, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended as the initial screening test.

The OAT Assists in Evaluating:

  • Krebs Cycle Abnormalities
  • Neurotransmitter Levels
  • Nutritional Deficiencies
  • Antioxidant Deficiencies
  • Yeast and Clostridia Overgrowth
  • Fatty Acid Metabolism
  • Oxalate Levels
  • And More

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Testing Organic Acids and Assessing the Methylation Cycle

Organic acids are derived from the metabolic conversion of dietary protein, fats and carbohydrates, in addition to bacterial origin in the gut. These markers provide a unique profile into cellular energy status, neurotransmitter metabolism, nutrient deficiencies, intestinal bacterial metabolism and detoxification.

Urine Metabolic Acids – The Power of Accuracy

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Free Webinar

Interpretation of the Organic Acids Test on the Education Portal

In this 1 hour webinar Dr. Shaw explains the role of organic acids in human metabolism and provides a detailed guide on how to interpret results from the OAT.

Organic Acid Testing: A clinicians perspective
Elizma Lambert discusses the interpretation of Organic Acid Testing (OAT) Results