Choosing the Right Progesterone Prescription: A Discussion on OMP & Vaginal Progesterone

Dr. Felice Gersh and Dr. Jaclyn Smeaton

Episode 159 on the DUTCH Podcast

June 30 2026

In this episode, Dr. Felice Gersh joins host Dr. Jaclyn Smeaton and DUTCH founder Mark Newman for a deep-dive on progesterone: its physiological roles, concerns around standard-of-care prescribing practices, and more.

This discussion also explores:

  • Progesterone’s role as more than an endometrial protectant
  • Supraphysiologic allopregnanolone created by oral micronized progesterone
  • The physiological benefits of cyclic dosing versus continuous dosing
  • How the gut microbiome impacts progesterone metabolism
  • The need for more research on oral micronized progesterone and dosing methods

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