Gut Barrier Panel
KBMO is one of the few breakthrough labs to measure Complement as part of their Food Inflammation Testing, acquiring a more complete look at the patient’s reaction level compared to IgG testing alone.
Knowing the Complement reaction to foods is important as it gives an indication of which foods may be causing inflammation in the body. Also, if someone has IgG and Complement to a particular food, their IgG reaction may be heightened. As a CLIA certified lab, KBMO track reproducibility to ensure reliable results, every time.
Under founder Dr. Dorval’s leadership, KBMO’s approach to quality, accuracy and reproducibility has been based on their roots in the HIV testing arena, where there is no room for error.
- Combines IgG(1-4) with Complement (C3d)
- Option of 176 or 132 foods & additives
- Gut Barrier Panel with markers for Candida, Occuludin, Zonulin and LPS – (IgG 1-4 & C3d and IgA 1-2 included with FIT 176 or FIT 132 tests and also available as a stand-alone test)
- Personalised meal plan provided alongside the FIT132 and FIT176
- A low-cost option of 22 of the most commonly reactive foods is also available
- Exemplary industry accuracy using ELISA technology
- Easy blood-spot collection
- Easy to read, bar-graph report
- KBMO offer an app for the FIT 176 & FIT 132 tests which includes the full report and a personalised 7-day meal plan designed by KBMO’s nutritionist panel. KBMO send out an email with the links to the correct app, 14 days after the practitioner receives the result. The patient must have filled in the app section on the requisition form.
Food Sensitivities and related diseases affect at least 100 million people worldwide and cause a wide variety of illnesses ranging from skin rashes and headaches to chronic intestinal diseases.
Unbalanced or inadequate diets, enzyme deficiencies, stress, genetic predisposition, infections and inflammation, chemicals, drugs, environmental pollutants and toxins are all possible contributing factors in the development of food sensitivities. Research has shown that these factors may weaken both digestion as well as the protective defences in our intestinal tract allowing for allergens to more easily confront our overwhelmed immune system.
The Relevance of IgG + C3d
An IgG antibody reaction to a food is a delayed reaction (anywhere from several hours to days). Research has indicated that IgG antibodies produced in the blood against particular foods may promote certain inflammatory reactions within the body.
Testing for Complement (C3d) is a direct measurement of inflammation in the body – and is therefore a very important inclusion for any food inflammation test. Activation of Complement alongside high production of IgG antibodies makes it very clear as to what foods will need to be eliminated from your patient’s diet.
Commonly, we see patient results that show high IgG antibodies to many foods. Understanding which of these foods are actually causing your patient inflammation is crucial in avoiding an excessive elimination program, resulting in a more positive patient experience.
The Food Inflammation Test (FIT) by KBMO measures both IgG(1-4) and Complement (C3d) – combining them into one easy-to-understand bar reading.
IgG + C3d
Testing for Complement (C3d) is a direct measurement of inflammation in the body – and is therefore a very important inclusion for any food inflammation test. Activation of Complement alongside high production of IgG antibodies makes it very clear as to what foods will need to be eliminated from your patient’s diet. The Food Inflammation Test (FIT) by KBMO measures both IgG(1-4) and Complement (C3d) – combining them into one easy-to-understand bar graph.
KBMO measure and use any candida overgrowth in the stomach/ dysbiosis as a precursor to leaky gut occurrence. Candida albicans inhabits the skin, mucous membranes, and intestine. If a person is reactive to C. albicans, this is an indication that proteins from this organism have entered the blood stream through the gut wall. This happens when the gut becomes leaky due to food sensitivities from other foods or direct injury.
Zonulin is a marker of intestinal permeability, otherwise known as leaky gut. If a patient has elevated Zonulin levels, the normal regulation of the tight junctions is compromised. This Zonulin marker is unique to KBMO as it is the only Zonulin assay which does not cross react with haptoglobin, properdin or any complement fragments. They have achieved this by creating a unique recombinant zonulin protein. By measuring the Zonulin antibody, it makes the assay also uniquely stable to avoid the fluctuations reported in Zonulin protein assays.
Occludin is a marker of tight junction stabilisation and optimal barrier function. Elevated occludin indicates that the tight junctions are breaking down.
Lipopolysaccharides (LPS) are a major structural component of the outer membrane of gram-negative bacteria. Elevated levels of antibody against LPS may be indicative of Leaky Gut Syndrome and other gastrointestinal inflammatory diseases.